Face
5 min read
Author:
Nadia Rennie

What is the difference between Retinol and Tretinoin?

Written by
Nadia Rennie
Published on
July 20, 2023

What is the difference between
Retinol and Tretinoin?

Tretinoin and retinol are both derivatives of vitamin A and are commonly used in skincare products, but they have some differences in terms of their potency and how they affect the skin.

Tretinoin
  • Potency: Tretinoin, also known as retinoic acid, is a prescription-strength retinoid that is more potent than retinol. It is typically used to treat acne, reduce fine lines and wrinkles, and improve skin texture. Retinol, on the other hand, is a milder form of vitamin A and is available over-the-counter in skincare products. It is considered a cosmetic ingredient rather than a medication.
  • Conversion: When applied to the skin, retinol undergoes a conversion process within the skin cells to become retinoic acid (the active form of vitamin A). Tretinoin is already in the active form, so it does not require conversion.
  • Availability: Tretinoin is only available with a prescription from a healthcare professional. Here at the Cobham Clinic we are able to prescribe Tretinoin after an in depth skin consultation to ensure that it is safe and effective product choice for you. Following that, we can then decide which is the correct strength and frequency for you. Most people start on Tretinoin 0.05 cream every 2-3 nights. They then work up to a higher frequency and/or strength. However, if  you have more sensitive skin we might start you on a lower frequency and/or lower strength Tretinoin 0.025 cream. On the other hand, if your skin is used to active products, your may decide to start you on Tretinoin 0.1 cream. Ultimately, this treatment will be personalised to your skin and goals. Retinol, however, can be found in various skincare products available over-the-counter, including creams, serums, and lotions. Obagi offers Retinol 0.5, best for those new to skincare or those with sensitive skin, while Obagi Retinol 1.0 is available for those who are already familiar with Retinoids.
  • Skin tolerance: Tretinoin is generally more irritating to the skin compared to retinol. It can cause dryness, redness, peeling, and increased sensitivity, especially when first starting to use it. Retinol, being milder, usually has fewer side effects and is better tolerated by most people.
  • Effectiveness: Due to its higher potency, tretinoin tends to produce more dramatic results in treating acne, reducing wrinkles, and improving skin texture. Retinol may take longer to show visible effects and may be more suitable for individuals with sensitive skin or those looking for a milder approach to skincare.
Retinol
iIt's important to note that both tretinoin and retinol increase the skin's sensitivity to sunlight, so it's crucial to use them in conjunction with a broad spectrum sunscreen and follow proper sun protection measures.